pentobarbital will minimize the level or impact of netupitant/palonosetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Netupitant is principally metabolized by CYP3A4; stay clear of use in patients who're chronically working with a powerful CYP3A4 inducerA lousy night's snooze can mean a bad wor